Q 1975201166.     Read the following article regarding "Gene
therapy'' and answer the following questions.
The ultimate goal of gene therapy is the gene
replacement therapy. Gene replacement therapy
permits physiological regulation of the
transgenes and elimination of the possibility of
insertional activation of other cellular gene
which occur at the time of random integration of
the foreign gene. At present the current strategy
for gene therapy largely centres around gene
augmentatious therapy, where the foreign gene
replaces the defections or missing gene

(a) What is gene therapy?
(b) How is gene therapy being used in treating
ADA deficiency patients?
(c) Mention the cause and the bod/ system
affected by ADA deficiency in humans.
(d) Name the vector used for transferring ADA-DNA
into the recipients cells in humans.
Name the recipients cells.